Nasal Spray May Replace Injectable Dental Anesthesia



Researchers at the University of Buffalo have tested a nasal spray that could replace injectable anesthesia for most dental procedures.  If the succeeding clinical trials positively confirm the safety and efficacy of the anesthetic spray, the new technique could tremendously help millions of needle-fearing dental patients.

Kovacaine Mist, the nasal dental anesthetic spray under test was developed by St. Renatus, LLC, a research company in Colorado, USA. Results show that it was an effective anesthesia in four out of five patients.  A total of 45 adult patients, 18 years and older, who underwent restoration of one maxillary tooth, participated in the study.  The patients, who had nasal spray, did not need additional anesthesia to tolerate the pain of the dental procedure.

The spray was designed for use in hard-tissue procedures, such as crown preparation and fillings. It is to be administered through the nasal cavity. According to the manufacturer, it anesthetizes only the upper teeth without any effect on the patient’s lips and face.

More information about the study, titled “Safety and Efficacy of a Novel Nasal Spray for Maxillary Dental Anesthesia,” can be found at the July issue of the Journal of Dental Research. 

Trials are still needed to validate the research findings. A successful result could eliminate one major reason why many people don’t want to undergo certain dental procedures. The manufacturer, S. Renatus LLC, sees final approval of the drug by nest year.